NUTRIM INFORMATION FOR DOCTORS
Nutrim was developed in the 1990s by an internationally recognized food scientist at the USDA named Dr. George Inglett.1 The cholesterol-lowering effects of oats have been demonstrated in research for over fifty years.2 Research has also shown than oat and oat extracts decrease insulin response and encourage healthy blood sugar levels.3 Nutrim is concentrated with beta-glucans, the most beneficial part of oats.4 In contrast to simple oatmeal or oat bran, Nutrim contains beta-glucan that has been liberated from the nondigestible parts of the oat matrix, improving bioavailability and effectiveness.
The Nutrim product and dosing qualifies for the FDA heart health claim. Nutrim is a 100% whole food oat phytonutrient, so, like oats, it is well tolerated and accepted at high doses.
Mechanisms of Action:
Oat beta-glucans have been shown to increase bile synthesis and excretion.5 Bile is the main way in which the body disposes of cholesterol. Beta-glucans have been shown to bind to bile and carry it out of the body, keeping it from being reabsorbed.6
Oat beta-glucans have been shown to bind to dietary fats, such as saturated and trans-fatty acids, and carry them out of the body.7 Dietary saturated and trans-fatty acids have been associated with elevated cholesterol levels.
Oat beta-glucans are broken down by good bacteria, which creates beneficial compounds that have been shown to block the production of cholesterol.8 Oats and oat beta-glucan concentrates have also been shown to have beneficial effects on blood sugar balance9,10,11, blood pressure12,13 and satiety.14
FDA Heart Health Claim:
Nutrim qualifies for the FDA heart health claim, “Soluble fiber from foods such as Nutrim oat bran, as a part of a diet low in saturated fats and cholesterol, may reduce the risk of coronary heart disease.”
Nutrim has no other added ingredients in the powder besides concentrated oat bran. It has acquired a GRAS (Generally Recognized As Safe) status by the FDA. “A GRAS substance, therefore, is one that has a long, safe history of common use in foods, or that is determined to be safe based on proven science.” A GRAS substance is one which also”…has a proven track record of safety based either on a history of use before 1958 or on published scientific evidence, and that need not be approved by the FDA prior to being used.”15
There are no known contraindications. There have been no reports of overdose. Flatulence is occasionally reported with the use of oat beta-glucans.
One study utilized Nutrim at high doses (8 scoops/day) and stated it was well accepted and tolerated.16 This same study also showed Nutrim, along with moderate exercise and a diet low in saturated fat and high in monounsaturated fat, produced a significant increase in HDL cholesterol (27.8%) and a decrease in LDL cholesterol (27.3%) compared to the placebo group. The Nutrim group also experienced an improvement in their blood sugar and weight loss.
Another study using oat beta-glucans incorporated into a fruit drink not only showed it to be effective for lowering cholesterol, but it did not seem to have a negative effect on the plasma levels of fat soluble antioxidants.17
1 Ag Res Svc, Science Hall of Fame [https://agresearchmag.ars.usda.gov/1998/dec/nutrim]
2 De Groot AP, Luyken R, Pikaar NA. “Cholesterol-Lowering Effect Of Rolled Oats.” The Lancet, Letters To The Editor (10 Aug 1963): 303-304.
3 Biorklund M, et al. “Changes in serum lipids and postprandial glucose and insulin concentrations after consumption of beverages with β-glucans from oats or barley: a randomized dose-controlled trial.” Europ J of Clin Nutr 59.11 (2005): 1272-1281.
4 Behall KM, Scholfield DJ, Hallfrisch J. “Effect of beta-glucan level in oat fiber extracts on blood lipids in men and women.” J of Am College of Nutr 16 (1997) 46-51.
5 Lia A, et al. “Oat beta-glucan increases bile acid excretion and a fiber-rich barley fraction increases cholesterol excretion in ileostomy subjects.” Am Soc for Clin Nutr 62.6 (1995): 1245-1251.
6 Kerckhoffs D, Brouns F, Hornstra G, Mensink R. “Effects on the Human Serum Lipoprotein Profile of β-Glucans, Soy Protein and Isoflavones, Plant Sterols and Stanols, Garlic and Tocotrienols.” J Nutr 132 (2002): 2494-2505.
7 Drozdowski LA, Reimer RA, Temelli F, Bell RC, Vasanthan T, Thomson AB. “Beta-Glucan extracts inhibit the in vitro intestinal uptake of long-chain fatty acids and cholesterol and down-regulate genes involved in lipogenesis and lipid transport in rats.” J Nutr Biochem 21.8 (Aug 2010): 695-701.
8 Graziano R, et al. “Dietary Fibers and Cardiometabolic Diseases.” Int J Mol Sci 13 (2012) 1524-1540.
9 Lammert A, et al. “Clinical benefit of a short term dietary oatmeal intervention in patients with type 2 diabetes and severe insulin resistance: a pilot study.” Exp Clin Endocroinol Diabetes 116.2 (20 Dec 2007): 132-4. Abstract.
10 Hallfrisch J. Scholfield D, Behall K. “Diets containing soluble oat extracts improve glucose and insulin responses of moderately hypercholesterolemic men and women.” Am J Clin Nutr 61 (1995): 379-84.
11 Reyna-Villasmil N, et al. “Oat-derived β-Glucan Significantly Improves HDLC and Diminishes LDLC and Non-HDL Cholesterol in Overweight Individuals with Mild Hypercholesterolemia.” Am J of Therapeutics 14 (2007): 203-212.
12 Keenan JM, Pins JJ, Frazel C, Moran A, Turnquist L. “Oat ingestion reduces systolic and diastolic blood pressure in patients with mild and borderline hypertension: a pilot trial.” J Fam Pract 51.4 (Apr 2002): 369.
13 Pins JJ, Geleva D, Keenan JM, Frazel C, O’Conner PJ, Cherney LM. “Do whole-grain oat cereals reduce the need for antihypertensive medications and improve blood pressure control?” 51.4 (Apr 2002): 353-9.
14 Beck EJ, Tosh SM, Batterham MJ, Tasell LC, Huang XF. “Oat beta-glucan increases postprandial cholecystokinin levels, decreases insulin response and extends subjective satiety in overweight subjects.” 53.10 (Oct 2009): 1343-51.
16 Reyna-Villasmil N, et al. “Oat-derived β-Glucan Significantly Improves HDLC and Diminishes LDLC and Non-HDL Cholesterol in Overweight Individuals with Mild Hypercholesterolemia.” Am J of Therapeutics 14 (2007): 203-212.
17. Naumann E, et al. “β-Glucan incorporated into a fruit drink effectively lowers serum LDL-cholesterol concentrations.” Am J Clin Nutr 83 (2006): 601-5.
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WHAT IS NUTRIM?
Nutrim is 100% natural soluble fiber from oat bran containing at least 10% beta-glucan. 50 years of research show eating oat bran helps control cholesterol. Nutrim's patented processing frees oat bran's most powerful factor — beta-glucan, greatly magnifying the potency of the bran. As a tasteless powder, Nutrim mixes easily with foods and beverages without compromising taste.
NINETY DAY WARRANTY
Nutrim oat beta-glucan is really one of those products you have to try to believe. We want you to feel safe ordering with us and for that reason each product we sell comes with a ninety day warranty. Order our Nutrim brand products today, and if you are unsatisfied in any way, simply give us a call within ninety days, and we'll be happy to refund 100% of your purchase price.
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